Azelaic acid is a naturally occurring compound found in whole grain cereals and certain animal products. It is also produced by the yeast Malassezia furfur, which is a normal inhabitant of the skin. Azelaic acid is used as a topical treatment for mild to moderate acne and rosacea. It works by reducing the production of keratin, a protein that can block pores and lead to acne, and by decreasing the growth of the bacteria that cause acne. It also has anti-inflammatory properties, which can help reduce the redness and swelling associated with rosacea. Azelaic acid is available as a cream, gel, or foam, and is typically applied twice a day to the affected area. It may take several weeks or even months to see improvement in your skin. Side effects are generally mild and may include itching, burning, or tingling. In rare cases, azelaic acid can cause a rash or hives. If you experience any of these side effects, stop using the medication and contact your doctor.
Azelaic acid is a naturally occurring dicarboxylic acid that has been shown to be effective in the treatment of a variety of skin conditions, including acne, rosacea, and melasma. It works by reducing the growth of certain bacteria that contribute to the development of these conditions, as well as by decreasing the formation of keratin, a protein that can block pores and lead to acne.
There have been several studies that have investigated the effectiveness of azelaic acid in treating these conditions. One study, published in the Journal of the American Academy of Dermatology in 2002, found that a 20% azelaic acid cream was effective in reducing the number of inflammatory acne lesions. Another study, published in the British Journal of Dermatology in 1994, found that a 15% azelaic acid gel was effective in reducing the severity of rosacea symptoms.
A more recent study, published in the Journal of Dermatological Treatment in 2019, found that a 10% azelaic acid gel was effective in improving the appearance of melasma, a condition characterized by dark, discolored patches on the skin. The study found that the azelaic acid gel was as effective as hydroquinone, a commonly used treatment for melasma, but with fewer side effects. overall, these studies suggest that azelaic acid is an effective treatment option for a variety of skin conditions